Acute Kidney Injury - Epidemiologic Prospective Investigation (AKI-EPI)

Acute Kidney Injury (AKI) is an important complication in ICU patients. It has a high incidence: 5 to 10 % of patients are treated with renal replacement therapy, and up to 2/3rd of ICU patients have at least a mild form of AKI. Also, AKI is associated with increased in-hospital death. Epidemiologic data on AKI using latest definitions are however lacking.

RIFLE is a recent developed consensus classification for Acute Kidney Injury and was accepted by the major nephrological and critical care societies. Therefore, the RIFLE classification offers an excellent tool to gather epidemiologic information on Acute Kidney Injury.

Management of early AKI is highly variable around the world and little data exist on the use therapies and the timing of renal replacement. This information is critical for the planning of future interventional trials and to understand the size of this problem.

The AKI-EPI trial is a worldwide collaborative trial on the epidemiology of AKI in ICU patients under the auspices of the Acute Kidney Injury Network (AKIN) and the European Critical Care Research Network (ECCRN). Data entry for the trial is minimal.

When you are interested you can find here info:   Detailed information  FORMS